The guiding rule.

Exchange server 2013+ and Outlook version 2013+ support Microsoft Office Add-ins.

Hence, if your company has Exchange 2010 and Outlook 2016. Your company will not be able to use Office add-ins from Outlook. Because minimum requirements are Exchange server 2013.

Microsoft resources available:

Outlook add-in deployment

For on-premises and online environments, you can deploy Outlook add-ins via the Exchange server.

Outlook add-in deployment requires:

  • Office 365, Exchange Online, or Exchange Server 2013 or later
  • Outlook 2013 or later

To assign add-ins to tenants, you use the Exchange admin center to upload a manifest directly, either from a file or a URL, or add an add-in from AppSource. To assign add-ins to individual users, you must use Exchange PowerShell. For details, see Install or remove Outlook add-ins for your organization.

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